The airport of Lisbon, located 37 Km away from the Grande Real Villa Itália Hotel & Spa, operates flights to and from Lisbon and to the main European cities with more than 50 airlines. The Aerobus service serves regular connections between the airport of Lisbon, several points in the city centre, bus and train terminals. The Hotel has a transfer service to the airport and vice-versa at an additional fee. This service has to be booked in advance at the Reservation Department.

The metropolitan region of Lisbon provides several national and international railway connections. The Hotel is at 1,6 km walking distance from the train station of Cascais of Cascais train line, that serve the city of Lisbon.

Urban public transports are provided by Scotturb and buses. In front of the hotel is a Scotturb bus stop taking you to the centre of Cascais, taking you to multiple destinations like Lisbon, or Sintra.

The Grande Real Villa Itália Hotel & Spa is located 1km, walk distance, from the centre of Cascais, where you can move around by car (taxi or rent-a-car), by bicycle, bus or on foot. Cascais has direct motorway connections to Lisbon or Sintra or to other locations as the South, Center and North of the Country.